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Georgia Journal of Science

Article Title

Enzyme-catalyzed Henry reaction

Abstract

The Henry reaction is an important chemical reaction in organic synthesis as it affords important building blocks. The Henry reaction produces beta-nitroalcohols under mild conditions. However this reaction usually has a low yield due the the presence of nitroalkenes, formed by dehydration of the beta-nitroalcohols during a further reaction. In order to increase the yield and to decrease the production of the nitro-alkene, several enzymes have been tested. In some cases, the biocatalyst afforded the desired alchol and in some other cases there was no reaction. A detailed report of which enzymes were an effective catalyst is presented in this work.

Acknowledgements

UWG SRAP, LSAMP, UWG COSM FRG

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