Enzyme-catalyzed Henry reaction

Authors

Anne C. Gaquere-Parker, University of West GeorgiaFollow

Abstract

The Henry reaction is an important chemical reaction in organic synthesis as it affords important building blocks. The Henry reaction produces beta-nitroalcohols under mild conditions. However this reaction usually has a low yield due the the presence of nitroalkenes, formed by dehydration of the beta-nitroalcohols during a further reaction. In order to increase the yield and to decrease the production of the nitro-alkene, several enzymes have been tested. In some cases, the biocatalyst afforded the desired alchol and in some other cases there was no reaction. A detailed report of which enzymes were an effective catalyst is presented in this work.

Acknowledgements

UWG SRAP, LSAMP, UWG COSM FRG

Recommended Citation

Gaquere-Parker, Anne C. (2018) "Enzyme-catalyzed Henry reaction," Georgia Journal of Science, Vol. 76, No. 1, Article 120.
Available at: https://digitalcommons.gaacademy.org/gjs/vol76/iss1/120