AN OPTIMIZATION OF TIME IN THE BROMINATION OF VANILLIN REACTION**
The bromination of aromatic rings is a common and useful reaction in classroom and industry settings. One example of this reaction, that organic chemistry students learn, is the electrophilic aromatic substitution of vanillin to produce bromovanillin. Vanillin contains multiple substituents that have differing directing properties so it is an ideal reagent for regio-chemistry analysis. This particular reaction is also practical because it can be run in a variety of ways and the reagents are fairly inexpensive. In order to avoid the use of elemental bromine, bromine was formed in situ with potassium bromate in the presence of acetic acid. The goal of this project was to optimize the time of this bromination reaction while still maintaining product purity and yield. The reaction was run for 5, 15, 25, 35, and 45 minutes at a time. Each reaction product was then assessed for percent yield and product purity. The results will be presented and discussed.
Piedmont Natural Science Department
Lowe*, Chandler and Bailey, Elaine
"AN OPTIMIZATION OF TIME IN THE BROMINATION OF VANILLIN REACTION**,"
Georgia Journal of Science, Vol. 81, No. 1, Article 69.
Available at: https://digitalcommons.gaacademy.org/gjs/vol81/iss1/69