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CELLULAR AND MOLECULAR BASES OF TRAUMA-RELATED ROOT RESORPTION

Abstract

Permanent teeth rarely undergo root resorption since the cementum covering on dentin is an essential element in the resistance of the dental root to resorption. It has been documented that osteoclasts will not adhere to or resorb non-mineralized osseous tissues. However, once the bone matrix is mineralized due to repair following dental trauma, RANKL/RANK/OPG system activate osteoclasts leading to bone resorption. Root resorption, not detected by conventional radiography typically remains asymptomatic, compromises tooth structure and eventually causes tooth loss. This paper reviews the pathophysiology of root resorption and presents a case study in which the apex and circumferential resorption resulted in a root shortening that exceeded 56%. The paper suggests that the extent of root resorption depends on the magnitude of the destruction, the tissue types involved, and the resorption duration.

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